GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE337nnn/GSE337706/primaryOK200TranscriptomicsHomo sapiensExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE337706GEOGSEfalseExploring Platelet-Covered and Naked Circulating Tumor Cells: A Single-Cell Transcriptomic Perspective [scRNA-seq Singleron]Circulating tumor cells (CTCs) and platelets can be collected simultaneously during liquid biopsy; however, their interaction in the form of platelet-covered CTCs (pcCTCs) remains only partially understood. This submission contains single-cell RNA sequencing data generated from PBMC/buffy coat fractions from 29 donors: 12 patients with high-grade serous ovarian carcinoma, 4 non-malignant gynecological controls, 10 patients with breast cancer, and 3 healthy donor controls. The dataset was used to detect and characterize candidate naked CTCs and pcCTCs and to compare their transcriptomic profiles with platelet and cancer-related signatures.2026/07/14GSE337706GSM9859780GSM9859771GSM9859770GSM9859773GSM9859772GSM9859775GSM9859774GSM9859777GSM9859776GSM9859779GSM9859768GSM9859778GSM985976934281337706Homo sapiens