{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE338nnn/GSE338150/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Genomics"],"species":["Mus musculus"],"gds_type":["Genome binding/occupancy profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE338150"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Chip seq data of transcription factor ELF-1 in mouse BMDM derived macrophages.","description":"Acute kidney injury (AKI) is an unavoidable complication following renal transplantation and a critical determinant of patient prognosis. M1-polarized macrophages are known to exacerbate the progression of AKI. Preliminary clinical data reveal a positive correlation between the expression level of E74-like ETS transcription factor 1 (ELF-1) in macrophages from post-transplant patients and the levels of pro-inflammatory cytokines. However, the role of ELF-1 in M1 macrophage polarization and the pathogenesis of AKI remains unclear. In this study, we aim to investigate the role of ELF-1 in M1 macrophage polarization and AKI pathogenesis by employing ELF-1-deficient murine macrophages and performing ChIP-seq to identify downstream genes regulated by ELF-1.","dates":{"publication":"2026/07/09"},"accession":"GSE338150","cross_references":{"GSM":["GSM9867944","GSM9867942","GSM9867943","GSM9867941"],"GPL":["24247"],"GSE":["338150"],"taxon":["Mus musculus"]}}