{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE338nnn/GSE338493/"]},"type":"primary"},"statusCodeValue":200,"statusCode":"OK"}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Homo sapiens"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE338493"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Transcriptomic profiling reveals IGF2BP1-mediated gene regulation and Helicobacter pylori-induced transcriptional reprogramming in gastric epithelial cells","description":"Helicobacter pylori infection induces persistent transcriptional reprogramming in gastric epithelial cells. To identify downstream pathways regulated by IGF2BP1, RNA sequencing was performed in GES-1 cells with IGF2BP1 overexpression and H. pylori infection. Integrated analysis identified overlapping transcriptional programs associated with oxidative stress regulation and ferroptosis-related pathways.","dates":{"publication":"2026/07/29"},"accession":"GSE338493","cross_references":{"GSM":["GSM9875647","GSM9875646","GSM9875645","GSM9875644","GSM9875649","GSM9875648","GSM9875650","GSM9875643","GSM9875642","GSM9875641","GSM9875651"],"GPL":["24676"],"GSE":["338493"],"taxon":["Homo sapiens"]}}