GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE338nnn/GSE338556/primary200OKTranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE338556GEOGSEfalseSingle-cell RNA sequencing of mouse peripheral blood neutrophils before and one day after corneal injuryNeutrophils are rapidly mobilized into circulation following sterile tissue injury, but the transcriptional heterogeneity of the peripheral blood neutrophil pool during this response is incompletely defined. To characterize how corneal injury reshapes the circulating neutrophil compartment, we performed droplet-based single-cell RNA sequencing on FACS-sorted peripheral blood neutrophils from mice at steady state (Pre-injury, normal) and one day after corneal injury (Day 1 post-corneal injury). Comparative analysis resolved distinct neutrophil states and revealed injury-associated shifts in subset composition. These data define the circulating neutrophil response to remote sterile corneal injury at single-cell resolution.2026/08/30GSE338556GSM9877214GSM987721524247338556Mus musculus