{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE338nnn/GSE338716/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Homo sapiens"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE338716"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Time-dependent BMP4 signaling directs lineage specification in human mesoderm","description":"We investigated the mechanisms underlying mesodermal heterogeneity using a minimal directed differentiation system that simultaneously generates paraxial, intermediate and lateral plate mesoderm populations. Single-cell RNA sequencing across defined time points during hPSC differentiation (from day (D)3 to D9) revealed a temporal sequence of lineage specification with the lateral plate mesoderm emerging first, followed by paraxial and intermediate mesoderm differentiation.","dates":{"publication":"2026/09/01"},"accession":"GSE338716","cross_references":{"GSM":["GSM9880549","GSM9880548","GSM9880547","GSM9880546","GSM9880551","GSM9880550"],"GPL":["24676"],"GSE":["338716"],"taxon":["Homo sapiens"]}}