GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE338nnn/GSE338747/primaryOK200Methylation profilingHomo sapiensMethylation profiling by genome tiling arrayhttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE338747GEOGSEfalseNanopore and EPIC Array Profiling Unmask an Atypical Non-Midline H3 K27-Altered Glioma: a case reportWe report a rare adult case of H3K27-altered diffuse glioma arising in an atypical non-midline location, highlighting the diagnostic challenges posed by its radiological and histopathological resemblance to glioblastoma. The study demonstrates the clinical utility of integrated histopathological, methylation-based, and genomic analyses, including rapid Nanopore methylation profiling, for accurate tumor classification and precision neuro-oncology. These findings are of direct relevance to neuropathologists, molecular pathologists, neurooncologists, and translational neuroscience researchers.2026/09/02GSE338747GSM988082833022338747Homo sapiens[42656225]