{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE338nnn/GSE338874/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Genomics"],"species":["Mus musculus"],"gds_type":["Genome binding/occupancy profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE338874"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"The Histone Demethylase KDM6B Restrains Hypermetabolic LYVE1+ Perivascular Macrophages and Preserves Adipogenic Balance [CUT&Tag pvm]","description":"We employed CUT&Tag sequencing to study H3K27me3 chromatin profiles in epididymal white adipose tissue perivascular macrophages isolated from wild-type and macrophage-specific KDM6B knockout mice fed a high-fat diet for 5 weeks. This study was designed to identify genotype-dependent changes in the repressive H3K27me3 mark associated with KDM6B deficiency during early diet-induced obesity.","dates":{"publication":"2026/09/01"},"accession":"GSE338874","cross_references":{"GSM":["GSM9883946","GSM9883947","GSM9883948","GSM9883949","GSM9883939","GSM9883950","GSM9883940","GSM9883951","GSM9883952","GSM9883941","GSM9883953","GSM9883942","GSM9883943","GSM9883944","GSM9883945"],"GPL":["24247"],"GSE":["338874"],"taxon":["Mus musculus"]}}