{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE339nnn/GSE339143/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Other"],"species":["Mus musculus"],"gds_type":[" Expression profiling by high throughput sequencing","Other"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE339143"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Targeting epigenetic rheostat Zmynd8 unleashes IL-2 signaling to override T cell exhaustion [scCRISPR]","description":"The gene regulatory network (GRN) underlying CD8+ T cell differentiation in chronic infection and whether Tex responses can be functionally reinvigorated are incompletely understood. Here, we systematically mapped causal GRNs via single-cell CRISPR (scCRISPR) screens in vivo and discovered regulators for CD8+ T cell differentiation in chronic infection.","dates":{"publication":"2026/09/28"},"accession":"GSE339143","cross_references":{"GSM":["GSM9889073","GSM9889072","GSM9889071","GSM9889070","GSM9889066","GSM9889065","GSM9889064","GSM9889069","GSM9889068","GSM9889067"],"GPL":["21103"],"GSE":["339143"],"taxon":["Mus musculus"]}}