{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE339nnn/GSE339267/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE339267"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"The Histone Demethylase KDM6B Restrains Hypermetabolic LYVE1+ Perivascular Macrophages and Preserves Adipogenic Balance","description":"We employed bulk RNA sequencing to study adipose tissue macrophages isolated from epididymal white adipose tissue of wild-type and macrophage-specific KDM6B knockout mice fed a high-fat diet for 5 weeks. This study was designed to identify genotype-dependent transcriptional changes associated with KDM6B deficiency during early diet-induced obesity.","dates":{"publication":"2026/09/01"},"accession":"GSE339267","cross_references":{"GSM":["GSM9892164","GSM9892176","GSM9892165","GSM9892163","GSM9892172","GSM9892168","GSM9892166","GSM9892177","GSM9892178","GSM9892167"],"GPL":["24247"],"GSE":["339267"],"taxon":["Mus musculus"]}}