GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE341nnn/GSE341456/primaryOK200TranscriptomicsHomo sapiensExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE341456GEOGSEfalseTranscriptomic responses of HAP1 cells to Bu-DIF-3 and CP-DIF-3Dictyostelium differentiation-inducing factors (DIFs) and their derivatives regulate diverse cellular functions in mammalian cells, but the molecular responses elicited by individual derivatives remain incompletely understood. We performed RNA sequencing of HAP1 cells treated for 24 h with vehicle, 5 µM Bu-DIF-3, or 5 µM CP-DIF-3. This dataset enables comparison of the transcriptomic responses to the two DIF-3 derivatives, including stress-response, redox, metabolic, and autophagy-related pathways.2026/08/01GSE341456GSM9907079GSM9907078GSM9907086GSM9907084GSM9907085GSM9907082GSM9907083GSM9907080GSM990708124676341456Homo sapiens