{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE341nnn/GSE341505/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE341505"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Transplantation of endothelial progenitor cells attenuates pulmonary fibrosis via IFITM3-containing exosomes","description":"Pulmonary endothelial progenitor cells contribute to vascular regeneration, but their molecular characteristics in the adult lung remain incompletely defined. In this study, single-cell RNA sequencing was performed on endothelial cells isolated from adult wild-type mouse lungs. KIT-positive endothelial cells were stratified into Foxf1-positive capillary endothelial progenitor cells (capEPCs) and Foxf1-negative endothelial cells. Differential gene expression analysis identified Ifitm3 as highly enriched in capEPCs, supporting a role for the FOXF1–IFITM3 pathway in endothelial regeneration and pulmonary fibrosis.","dates":{"publication":"2026/08/13"},"accession":"GSE341505","cross_references":{"GSM":["GSM9907912"],"GPL":["24247"],"GSE":["341505"],"taxon":["Mus musculus"]}}