{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE342nnn/GSE342782/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Homo sapiens"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE342782"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Bulk RNA sequencing of human sensory neurons following varicella-zoster virus infection or exposure to patient-derived serum exosomes","description":"Bulk RNA sequencing was performed to characterize transcriptional responses of differentiated human sensory neurons following either direct varicella-zoster virus infection or exposure to serum-derived exosomes from healthy controls, patients with acute herpes zoster, or patients with post-herpetic neuralgia. These datasets were generated to identify molecular pathways associated with direct viral infection and exosome-mediated neuronal dysfunction. reference genome and gene quantification by RSEM. Differential expression and downstream pathway analyses were performed using DESeq2 and gene set enrichment analysis.","dates":{"publication":"2026/09/02"},"accession":"GSE342782","cross_references":{"GSM":["GSM9939206","GSM9939228","GSM9939227","GSM9939205","GSM9939208","GSM9939229","GSM9939207","GSM9939209","GSM9939220","GSM9939222","GSM9939221","GSM9939224","GSM9939223","GSM9939226","GSM9939225","GSM9939217","GSM9939216","GSM9939219","GSM9939218","GSM9939231","GSM9939230","GSM9939233","GSM9939211","GSM9939232","GSM9939210","GSM9939235","GSM9939213","GSM9939212","GSM9939234","GSM9939215","GSM9939214"],"GPL":["24676"],"GSE":["342782"],"taxon":["Homo sapiens"]}}