GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE342nnn/GSE342782/primaryOK200TranscriptomicsHomo sapiensExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE342782GEOGSEfalseBulk RNA sequencing of human sensory neurons following varicella-zoster virus infection or exposure to patient-derived serum exosomesBulk RNA sequencing was performed to characterize transcriptional responses of differentiated human sensory neurons following either direct varicella-zoster virus infection or exposure to serum-derived exosomes from healthy controls, patients with acute herpes zoster, or patients with post-herpetic neuralgia. These datasets were generated to identify molecular pathways associated with direct viral infection and exosome-mediated neuronal dysfunction. reference genome and gene quantification by RSEM. Differential expression and downstream pathway analyses were performed using DESeq2 and gene set enrichment analysis.2026/09/02GSE342782GSM9939206GSM9939228GSM9939227GSM9939205GSM9939208GSM9939229GSM9939207GSM9939209GSM9939220GSM9939222GSM9939221GSM9939224GSM9939223GSM9939226GSM9939225GSM9939217GSM9939216GSM9939219GSM9939218GSM9939231GSM9939230GSM9939233GSM9939211GSM9939232GSM9939210GSM9939235GSM9939213GSM9939212GSM9939234GSM9939215GSM993921424676342782Homo sapiens