{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE342nnn/GSE342961/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE342961"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Transcriptomic profiling (RNA-seq) of lung endothelial cells from wild-type (WT) and TET2KO mice following 28 days of Angiotensin II treatment.","description":"Chronic hypertension and Angiotensin II infusion induce systemic vascular and endothelial dysfunction. To investigate cell-autonomous transcriptional changes resulting from endothelial-specific TET2 deficiency in the pulmonary microenvironment, we performed total RNA sequencing on lung endothelial cells isolated from wild-type (WT) and endothelial-specific TET2 knockout (TET2KO) mice after 28 days of Angiotensin II treatment.","dates":{"publication":"2026/08/10"},"accession":"GSE342961","cross_references":{"GSM":["GSM9944068","GSM9944067","GSM9944064","GSM9944066","GSM9944065"],"GPL":["24247"],"GSE":["342961"],"taxon":["Mus musculus"]}}