{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE344nnn/GSE344032/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE344032"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Ptpn1 loss leads to B cell acute lymphoblastic leukemia","description":"Mice with NHD13 expression and homozygous Ptpn1 loss developed BCP-ALL with a penetrance of 70%, suggesting that Ptpn1 can function as a tumor suppressor gene in this context. Moreover, NHD13/Ptpn1+/- mice that developed BCP ALL typically showed a loss of the Ptpn1 wild type allele in leukemia cells, supporting the assertion that Ptpn1 can function as a tumor suppressor gene.","dates":{"publication":"2026/08/19"},"accession":"GSE344032","cross_references":{"GSM":["GSM9966730","GSM9966731","GSM9966732","GSM9966726","GSM9966727","GSM9966725","GSM9966728","GSM9966729"],"GPL":["24247"],"GSE":["344032"],"taxon":["Mus musculus"]}}