{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE344nnn/GSE344060/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Homo sapiens"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE344060"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Sex-related differences in gene expression contribute to recurrence in the post-operative ileum","description":"Question: How does gene expression in CD patients change after ileal resection, and what factors impact these expression changes? Findings: This study assessed RNA-seq and genetic components of 339 samples collected from recurring and non-recurring severe CD patients following ileal resection. We found that males have more pronounced changes in gene expression, with pathway analysis implicating divergent ESR1, ESR2, vs. PGR effects. Meaning: Sex-specific differences in gene expression have implications for tailored prediction, diagnosis, and treatment of patients.","dates":{"publication":"2026/08/18"},"accession":"GSE344060","cross_references":{"GSM":["GSM9967382","GSM9967381","GSM9967380","GSM9967386","GSM9967385","GSM9967384","GSM9967383","GSM9967389","GSM9967388","GSM9967387","GSM9967371","GSM9967492","GSM9967491","GSM9967370","GSM9967490","GSM9967496","GSM9967375","GSM9967495","GSM9967374","GSM9967373","GSM9967494","GSM9967493","GSM9967372","GSM9967379","GSM9967499","GSM9967378","GSM9967377","GSM9967498","GSM9967376","GSM9967497","GSM9967360","GSM9967481","GSM9967480","GSM9967485","GSM9967364","GSM9967363","GSM9967484","GSM9967362","GSM9967483","GSM9967482","GSM9967361","GSM9967368","GSM9967489","GSM9967488","GSM9967367","GSM9967366","GSM9967487","GSM9967365","GSM9967486","GSM9967369","GSM9967591","GSM9967470","GSM9967590","GSM9967353","GSM9967474","GSM9967595","GSM9967594","GSM9967352","GSM9967473","GSM9967472","GSM9967593","GSM9967592","GSM9967471","GSM9967357","GSM9967599","GSM9967478","GSM9967477","GSM9967356","GSM9967598","GSM9967476","GSM9967355","GSM9967597","GSM9967354","GSM9967475","GSM9967596","GSM9967359","GSM9967479","GSM9967358","GSM9967580","GSM9967463","GSM9967584","GSM9967583","GSM9967462","GSM9967582","GSM9967461","GSM9967460","GSM9967581","GSM9967588","GSM9967467","GSM9967466","GSM9967587","GSM9967465","GSM9967586","GSM9967585","GSM9967464","GSM9967469","GSM9967468","GSM9967589","GSM9967690","GSM9967573","GSM9967452","GSM9967451","GSM9967572","GSM9967571","GSM9967450","GSM9967570","GSM9967456","GSM9967577","GSM9967576","GSM9967455","GSM9967454","GSM9967575","GSM9967574","GSM9967453","GSM9967459","GSM9967458","GSM9967579","GSM9967578","GSM9967457","GSM9967562","GSM9967683","GSM9967441","GSM9967440","GSM9967682","GSM9967561","GSM9967560","GSM9967681","GSM9967680","GSM9967445","GSM9967566","GSM9967687","GSM9967565","GSM9967686","GSM9967444","GSM9967685","GSM9967443","GSM9967564","GSM9967442","GSM9967563","GSM9967684","GSM9967449","GSM9967448","GSM9967569","GSM9967568","GSM9967689","GSM9967447","GSM9967688","GSM9967567","GSM9967446","GSM9967551","GSM9967672","GSM9967430","GSM9967671","GSM9967550","GSM9967670","GSM9967434","GSM9967676","GSM9967555","GSM9967554","GSM9967675","GSM9967433","GSM9967674","GSM9967432","GSM9967553","GSM9967431","GSM9967673","GSM9967552","GSM9967438","GSM9967559","GSM9967437","GSM9967679","GSM9967558","GSM9967436","GSM9967557","GSM9967678","GSM9967677","GSM9967435","GSM9967556","GSM9967439","GSM9967540","GSM9967661","GSM9967660","GSM9967665","GSM9967423","GSM9967544","GSM9967422","GSM9967543","GSM9967664","GSM9967542","GSM9967663","GSM9967421","GSM9967541","GSM9967420","GSM9967662","GSM9967548","GSM9967669","GSM9967427","GSM9967668","GSM9967547","GSM9967426","GSM9967425","GSM9967546","GSM9967667","GSM9967666","GSM9967545","GSM9967424","GSM9967429","GSM9967428","GSM9967549","GSM9967650","GSM9967654","GSM9967412","GSM9967533","GSM9967411","GSM9967532","GSM9967653","GSM9967531","GSM9967652","GSM9967410","GSM9967651","GSM9967530","GSM9967416","GSM9967537","GSM9967658","GSM9967657","GSM9967415","GSM9967536","GSM9967414","GSM9967535","GSM9967656","GSM9967534","GSM9967655","GSM9967413","GSM9967419","GSM9967539","GSM9967418","GSM9967538","GSM9967417","GSM9967659","GSM9967522","GSM9967643","GSM9967401","GSM9967400","GSM9967521","GSM9967642","GSM9967520","GSM9967641","GSM9967640","GSM9967405","GSM9967647","GSM9967526","GSM9967525","GSM9967646","GSM9967404","GSM9967403","GSM9967645","GSM9967524","GSM9967402","GSM9967523","GSM9967644","GSM9967409","GSM9967408","GSM9967529","GSM9967528","GSM9967649","GSM9967407","GSM9967648","GSM9967406","GSM9967527","GSM9967511","GSM9967632","GSM9967631","GSM9967510","GSM9967630","GSM9967515","GSM9967636","GSM9967514","GSM9967635","GSM9967634","GSM9967513","GSM9967512","GSM9967633","GSM9967519","GSM9967518","GSM9967639","GSM9967517","GSM9967638","GSM9967637","GSM9967516","GSM9967500","GSM9967621","GSM9967620","GSM9967625","GSM9967504","GSM9967503","GSM9967624","GSM9967502","GSM9967623","GSM9967622","GSM9967501","GSM9967508","GSM9967629","GSM9967628","GSM9967507","GSM9967506","GSM9967627","GSM9967505","GSM9967626","GSM9967509","GSM9967610","GSM9967614","GSM9967613","GSM9967612","GSM9967611","GSM9967618","GSM9967617","GSM9967616","GSM9967615","GSM9967619","GSM9967603","GSM9967602","GSM9967601","GSM9967600","GSM9967607","GSM9967606","GSM9967605","GSM9967604","GSM9967609","GSM9967608","GSM9967393","GSM9967392","GSM9967391","GSM9967390","GSM9967397","GSM9967396","GSM9967395","GSM9967394","GSM9967399","GSM9967398"],"GPL":["24676"],"GSE":["344060"],"taxon":["Homo sapiens"],"PMID":["[41251630]"]}}