{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE344nnn/GSE344322/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Homo sapiens"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE344322"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Effect of glutamine deprivation on naïve CD4+ T cells differentiation","description":"Glutamine availability is a major determinant of T-cell metabolism and function. To define the transcriptional consequences of glutamine deprivation during human T-cell activation, we performed bulk RNA sequencing of naïve CD4+ T cells stimulated through the T-cell receptor under glutamine-free or physiological-range glutamine conditions. This dataset enables analysis of glutamine-dependent transcriptional programs in activated CD4+ T cells, including pathways related to cellular stress, redox regulation and inflammatory signalling.","dates":{"publication":"2026/08/23"},"accession":"GSE344322","cross_references":{"GSM":["GSM9975100","GSM9975101","GSM9975102","GSM9975103","GSM9975104","GSM9975105","GSM9975106","GSM9975107"],"GPL":["34295"],"GSE":["344322"],"taxon":["Homo sapiens"]}}