GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE344nnn/GSE344322/primary200OKTranscriptomicsHomo sapiensExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE344322GEOGSEfalseEffect of glutamine deprivation on naïve CD4+ T cells differentiationGlutamine availability is a major determinant of T-cell metabolism and function. To define the transcriptional consequences of glutamine deprivation during human T-cell activation, we performed bulk RNA sequencing of naïve CD4+ T cells stimulated through the T-cell receptor under glutamine-free or physiological-range glutamine conditions. This dataset enables analysis of glutamine-dependent transcriptional programs in activated CD4+ T cells, including pathways related to cellular stress, redox regulation and inflammatory signalling.2026/08/23GSE344322GSM9975100GSM9975101GSM9975102GSM9975103GSM9975104GSM9975105GSM9975106GSM997510734295344322Homo sapiens