GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE344nnn/GSE344516/primaryOK200TranscriptomicsHomo sapiensExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE344516GEOGSEfalseTranscriptomic profiling of YBX1 knockdown in human nucleus pulposus cellsIntervertebral disc degeneration is accompanied by extracellular matrix remodeling and inflammatory changes in nucleus pulposus cells. To characterize transcriptional changes associated with Y-box binding protein 1 (YBX1) depletion, bulk RNA sequencing was performed on primary human nucleus pulposus cells transfected with YBX1-targeting small interfering RNA or negative-control small interfering RNA. The dataset contains six libraries, comprising three biological replicates per condition.2026/08/22GSE344516GSM9980665GSM9980666GSM9980661GSM9980662GSM9980663GSM998066424676344516Homo sapiens