GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE344nnn/GSE344645/primaryOK200TranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE344645GEOGSEfalseMelatonin Ameliorates NEC-Associated Brain Injury by Suppressing Microglial M1 Polarization via the AMPK-IL-1β AxisNeonatal necrotizing enterocolitis (NEC) is a severe gastrointestinal disorder that poses a significant threat to neonatal survival. Among its numerous complications, NEC-associated brain injury is particularly detrimental, exerting profound adverse effects on long-term neurodevelopment and cognitive function in affected infants. However, the precise pathophysiological mechanisms underlying this neurological complication remain inadequately elucidated, and effective targeted therapeutic interventions are currently lacking. This study aims to investigate the key molecular and cellular pathways involved in the pathogenesis of NEC-related brain injury, with the ultimate goal of identifying novel research directions and potential therapeutic targets for its clinical prevention and management.2026/08/26GSE344645GSM9982700GSM9982696GSM9982697GSM9982698GSM9982699GSM998269524247344645Mus musculus