{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE344nnn/GSE344974/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE344974"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Prmt1-mediated Otud4 methylation activates the Pabpc1–Scube3 axis to promote bone formation and ameliorate osteoporosis","description":"Osteoporosis is a systemic skeletal disorder characterized by reduced bone mass, deteriorated bone microarchitecture, and elevated fracture risk due to an imbalance between osteoblast-mediated formation and osteoclast-driven resorption. Although protein arginine methyltransferase 1 (Prmt1) is implicated in skeletal metabolism, its precise functional role in osteoblast biology remains elusive.","dates":{"publication":"2026/08/31"},"accession":"GSE344974","cross_references":{"GSM":["GSM9989085","GSM9989086","GSM9989087"],"GPL":["24247"],"GSE":["344974"],"taxon":["Mus musculus"]}}