GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE345nnn/GSE345466/primaryOK200TranscriptomicsHomo sapiensExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE345466GEOGSEfalseDevelopmental Arrest Associated with Altered Cerebellar Metabolism in Sudden Infant Death SyndromeSudden infant death syndrome (SIDS) may involve impaired cerebellar contributions to autonomic and arousal responses during hypoxic stress. We performed bulk RNA sequencing of flash-frozen postmortem human cerebellar cortex from SIDS infants and age-matched non-SIDS controls to define transcriptional alterations associated with SIDS. Differential-expression and pathway-enrichment analyses were used to evaluate neuroinflammatory, neurotransmitter, and metabolic programs, and transcriptomic findings were compared at the pathway level with independently generated targeted metabolomics and quantitative histology data.2026/08/30GSE345466GSM10005134GSM10005145GSM10005144GSM10005133GSM10005136GSM10005135GSM10005146GSM10005141GSM10005130GSM10005140GSM10005132GSM10005143GSM10005142GSM10005131GSM10005138GSM10005137GSM10005129GSM1000513924676345466Homo sapiens