{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE345nnn/GSE345566/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE345566"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Microglial dysregulation promotes aberrant synaptic engulfment and CXCL10-associated CD8⁺ T-cell accumulation in CMT2A mice","description":"Charcot–Marie–Tooth disease type 2A (CMT2A), caused by pathogenic variants in MFN2, is primarily recognized as a peripheral axonopathy. Depression and psychological distress have also been reported in patients with CMT, but it remains unclear whether MFN2 mutations engage central neuroimmune mechanisms that affect behavior.","dates":{"publication":"2026/09/04"},"accession":"GSE345566","cross_references":{"GSM":["GSM10008930","GSM10008931","GSM10008929","GSM10008927","GSM10008928","GSM10008925","GSM10008926","GSM10008923","GSM10008924"],"GPL":["24247"],"GSE":["345566"],"taxon":["Mus musculus"]}}