GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE345nnn/GSE345566/primary200OKTranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE345566GEOGSEfalseMicroglial dysregulation promotes aberrant synaptic engulfment and CXCL10-associated CD8⁺ T-cell accumulation in CMT2A miceCharcot–Marie–Tooth disease type 2A (CMT2A), caused by pathogenic variants in MFN2, is primarily recognized as a peripheral axonopathy. Depression and psychological distress have also been reported in patients with CMT, but it remains unclear whether MFN2 mutations engage central neuroimmune mechanisms that affect behavior.2026/09/04GSE345566GSM10008930GSM10008931GSM10008929GSM10008927GSM10008928GSM10008925GSM10008926GSM10008923GSM1000892424247345566Mus musculus