{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE345nnn/GSE345593/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE345593"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Kidney transcriptome of aged and young wild-type mice (RNA-seq)","description":"RNA-sequencing of kidney tissue from aged (28-32 months) and young (3 months) wild-type C57BL/6J mice, used to characterize transcriptional changes associated with natural aging. Kidney was collected for bulk RNA-seq to compare age-related transcriptional changes to those observed with chronic NAD deficiency in ANDY mice fed a niacin-free diet (NFD vs CD; deposited separately as the recovery_kidney SubSeries). This dataset was generated in support of: Benitez-Rosendo, A. & Feuz, M. B. et al. 'Inducible chronic NAD deficiency in mice reveals multi-systemic phenotypical, metabolic, and transcriptional changes.' Nature Communications (in revision; NCOMMS-26-053722-T) (Fig. 6e-h).","dates":{"publication":"2026/09/08"},"accession":"GSE345593","cross_references":{"GSM":["GSM10011380","GSM10011382","GSM10011381","GSM10011384","GSM10011383","GSM10011386","GSM10011385","GSM10011377","GSM10011387","GSM10011376","GSM10011379","GSM10011378"],"GPL":["30172"],"GSE":["345593"],"taxon":["Mus musculus"]}}