GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE345nnn/GSE345593/primaryOK200TranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE345593GEOGSEfalseKidney transcriptome of aged and young wild-type mice (RNA-seq)RNA-sequencing of kidney tissue from aged (28-32 months) and young (3 months) wild-type C57BL/6J mice, used to characterize transcriptional changes associated with natural aging. Kidney was collected for bulk RNA-seq to compare age-related transcriptional changes to those observed with chronic NAD deficiency in ANDY mice fed a niacin-free diet (NFD vs CD; deposited separately as the recovery_kidney SubSeries). This dataset was generated in support of: Benitez-Rosendo, A. & Feuz, M. B. et al. 'Inducible chronic NAD deficiency in mice reveals multi-systemic phenotypical, metabolic, and transcriptional changes.' Nature Communications (in revision; NCOMMS-26-053722-T) (Fig. 6e-h).2026/09/08GSE345593GSM10011380GSM10011382GSM10011381GSM10011384GSM10011383GSM10011386GSM10011385GSM10011377GSM10011387GSM10011376GSM10011379GSM1001137830172345593Mus musculus