{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE345nnn/GSE345749/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Rattus norvegicus"],"gds_type":["Expression profiling by array"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE345749"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Transcriptomic profiling of CCL2-high and CCL2-low glioma cell states","description":"Glioma cells can reversibly occupy cellular states with distinct contributions to tumor growth and microenvironmental remodelling. To define transcriptional programmes associated with endogenous Ccl2 activity, CCL2-high and CCL2-low cells were isolated from endogenous Ccl2 reporter cells by fluorescence-activated cell sorting and analysed using one-colour gene-expression microarrays. The resulting profiles were used to identify genes and pathways preferentially represented in the CCL2-high niche-remodelling state or the CCL2-low proliferative state.","dates":{"publication":"2026/09/06"},"accession":"GSE345749","cross_references":{"GSM":["GSM10015922","GSM10015921"],"GPL":["22740"],"GSE":["345749"],"taxon":["Rattus norvegicus"]}}