GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE345nnn/GSE345972/primaryOK200TranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE345972GEOGSEfalseTranscriptomic analysis of the effects of Poly I:C on islet cells in NOD miceThe relationship of autoimmune type 1 diabetes (T1D) and natural killer (NK) cells remains unclear. Poly inosine:cytidine (PolyI:C) is a double-stranded RNA mimic that activates an anti-viral response through TLR3 signaling and leads to activation of NK cells. Here we administered PolyI:C to female NOD mice in order to understand how NK cell activation changes the islet microenvironment by altering transcriptomes of islet cells.2026/09/14GSE345972GSM10020079GSM10020078GSM10020077GSM10020076GSM10020075GSM10020074GSM10020084GSM10020083GSM10020082GSM10020081GSM1002008021103345972Mus musculus