GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE346nnn/GSE346756/primary200OKTranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE346756GEOGSEfalseMaternal Exposure to Fructose, Sucrose, and Erythritol Impairs Renal Development and Function in Mouse OffspringMaternal exposure to sweeteners during gestation and lactation may influence renal development and function in offspring. In this study, we investigated transcriptomic alterations in the renal cortex of 3-week-old male mouse offspring following maternal exposure to fructose, sucrose, or erythritol. Pregnant C57BL/6J mice were randomly assigned to four groups receiving drinking water, 20% (w/v) fructose, 20% (w/v) sucrose, or 20% (w/v) erythritol throughout gestation and lactation. Renal cortical tissues from male offspring at 3 weeks of age were collected for RNA sequencing. Differentially expressed genes and enriched biological pathways were analyzed to characterize transcriptomic changes associated with maternal sweetener exposure.2026/09/15GSE346756GSM10040098GSM10040087GSM10040097GSM10040096GSM10040095GSM10040089GSM10040088GSM10040090GSM10040094GSM10040093GSM10040092GSM1004009124247346756Mus musculus