GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE346nnn/GSE346990/primary200OKTranscriptomicsLacticaseibacillus paracaseiExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE346990GEOGSEfalseDynamic Supramolecular Hydrogel Reprogram Probiotic Metabolism and Enhance Therapeutic Efficacy in PeriodontitisHydrogel network dynamics can influence the biological function of encapsulated probiotics. We performed RNA sequencing to compare the transcriptional profiles of Lacticaseibacillus paracasei encapsulated in dynamic supramolecular (Lp@PP) and static covalently crosslinked (Lp@BM) hydrogels. Our analysis revealed distinct growth-associated and stress-adaptive transcriptional programs in Lp@PP and Lp@BM, respectively.2026/09/20GSE346990GSM10043730GSM10043731GSM10043732GSM10043729GSM10043733GSM1004373434642346990Lacticaseibacillus paracasei