{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE347nnn/GSE347263/"]},"type":"primary"},"statusCodeValue":200,"statusCode":"OK"}],"scores":null,"additional":{"omics_type":["Methylation profiling"],"species":["Homo sapiens"],"gds_type":["Methylation profiling by genome tiling array"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE347263"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Decitabine-induced CD38 upregulation augments daratumumab activity in xenograft T-ALL","description":"This study investigates epigenetic regulation of CD38 in T-cell acute lymphoblastic leukemia (T-ALL) and the effect of decitabine (DEC) on CD38 promoter methylation and CD38 expression. Genome-wide DNA methylation profiling was performed in T-ALL cell lines treated with DEC or DMSO and in baseline T-ALL patient-derived xenograft (PDX) samples using the Illumina Infinium MethylationEPIC BeadChip v2.0.","dates":{"publication":"2026/09/15"},"accession":"GSE347263","cross_references":{"GSM":["GSM10048123","GSM10048112","GSM10048124","GSM10048113","GSM10048121","GSM10048110","GSM10048111","GSM10048122","GSM10048120","GSM10048109","GSM10048118","GSM10048108","GSM10048119","GSM10048116","GSM10048117","GSM10048114","GSM10048125","GSM10048126","GSM10048115"],"GPL":["33022"],"GSE":["347263"],"taxon":["Homo sapiens"]}}