{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE347nnn/GSE347514/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by array"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE347514"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Cxcr2 deficiency alters transcriptional programs in articular cartilage and subchondral bone of adult male mice","description":"C-X-C chemokine receptor 2 (CXCR2) regulates leukocyte trafficking and inflammatory signaling, but its contribution to skeletal homeostasis across bone-related tissues is incompletely understood. We profiled gene expression in femoral head articular cartilage and knee subchondral bone from adult male Cxcr2-null mice and wild-type littermate controls using Clariom S Mouse microarrays. The microarray dataset is part of a multi-tissue study linking Cxcr2 deficiency to altered bone microarchitecture and coordinated, tissue-specific transcriptional remodeling in bone marrow, articular cartilage, and subchondral bone.","dates":{"publication":"2026/09/21"},"accession":"GSE347514","cross_references":{"GSM":["GSM10054574","GSM10054573","GSM10054572","GSM10054571","GSM10054567","GSM10054566","GSM10054565","GSM10054576","GSM10054575","GSM10054569","GSM10054568","GSM10054570"],"GPL":["23038"],"GSE":["347514"],"taxon":["Mus musculus"]}}