{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE347nnn/GSE347847/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Genomics"],"species":["Homo sapiens"],"gds_type":["Genome binding/occupancy profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE347847"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Single-cell ATAC-seq profiling of ARID1A-loss-associated chromatin accessibility heterogeneity in pancreatic cancer cells","description":"This Series contains single-cell ATAC-seq datasets from clone-resolved and pooled perturbation experiments examining how ARID1A and other epigenetic modifiers influence chromatin-accessibility heterogeneity in pancreatic ductal adenocarcinoma cells. The datasets include the main 28-clone BxPC3 experiment, a large-scale pooled five-shRNA experiment, acute SMARCA4 degradation with AU-15330, and independent experiments in BxPC3, HPAC/HPAFII, SW1990, and SUIT-2 backgrounds. PseuMO-Tag lineage barcodes were used to connect single-cell chromatin profiles to clonal identity.","dates":{"publication":"2026/09/22"},"accession":"GSE347847","cross_references":{"GSM":["GSM10061726","GSM10061727","GSM10061728","GSM10061729","GSM10061719","GSM10061730","GSM10061731","GSM10061720","GSM10061732","GSM10061721","GSM10061733","GSM10061722","GSM10061723","GSM10061724","GSM10061725"],"GPL":["21697"],"GSE":["347847"],"taxon":["Homo sapiens"]}}