GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE347nnn/GSE347847/primary200OKGenomicsHomo sapiensGenome binding/occupancy profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE347847GEOGSEfalseSingle-cell ATAC-seq profiling of ARID1A-loss-associated chromatin accessibility heterogeneity in pancreatic cancer cellsThis Series contains single-cell ATAC-seq datasets from clone-resolved and pooled perturbation experiments examining how ARID1A and other epigenetic modifiers influence chromatin-accessibility heterogeneity in pancreatic ductal adenocarcinoma cells. The datasets include the main 28-clone BxPC3 experiment, a large-scale pooled five-shRNA experiment, acute SMARCA4 degradation with AU-15330, and independent experiments in BxPC3, HPAC/HPAFII, SW1990, and SUIT-2 backgrounds. PseuMO-Tag lineage barcodes were used to connect single-cell chromatin profiles to clonal identity.2026/09/22GSE347847GSM10061726GSM10061727GSM10061728GSM10061729GSM10061719GSM10061730GSM10061731GSM10061720GSM10061732GSM10061721GSM10061733GSM10061722GSM10061723GSM10061724GSM1006172521697347847Homo sapiens