{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE347nnn/GSE347933/"]},"type":"primary"},"statusCodeValue":200,"statusCode":"OK"}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE347933"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Myeloid Cell COX-2 Deficiency Exacerbated Salt-Sensitive Hypertension [RNA-Seq]","description":"It is well known that either nonselective (NSAIDs) or selective inhibitors of cyclooxygenase -2 (COX-2) will promote and/or exacerbate hypertension, especially in salt-sensitive individuals. Although previous studies have indicated that COX-2 inhibition of intrinsic kidney cells can modify kidney epithelial sodium transport, our previous studies demonstrated that deletion of COX-2 in hematopoietic cells also led to blood pressure increases in mice in response to a high salt diet.","dates":{"publication":"2026/09/23"},"accession":"GSE347933","cross_references":{"GSM":["GSM10062919","GSM10062920","GSM10062921","GSM10062922","GSM10062923","GSM10062924"],"GPL":["24247"],"GSE":["347933"],"taxon":["Mus musculus"]}}