GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE349nnn/GSE349044/primary200OKTranscriptomicsHomo sapiensExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE349044GEOGSEfalseSpatial and functional heterogeneity of cancer-associated fibroblasts at the tumor center and invasive tumor front of oral squamous cell carcinoma with distinct worst patterns of invasionThe worst pattern of invasion (WPOI) is an established prognostic feature in oral squamous cell carcinoma (OSCC), but the spatial contribution of cancer-associated fibroblasts (CAFs) to highly invasive WPOI4-5 tumors remains unclear. We performed bulk RNA sequencing of paired CAFs isolated from the tumor center and invasive tumor front of two WPOI1-3 and two WPOI4-5 OSCC tumors. This dataset supports paired analyses of regional expression differences and the WPOI-by-region interaction.2026/10/04GSE349044GSM10086194GSM10086192GSM10086193GSM10086190GSM10086191GSM10086189GSM10086187GSM1008618829480349044Homo sapiens