GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE349nnn/GSE349121/primaryOK200TranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE349121GEOGSEfalseTranscriptome profiling of synovial fibroblasts with ACOX1 overexpressionThis RNA-seq dataset was generated to investigate the transcriptional changes induced by ACOX1 overexpression in synovial fibroblasts. Synovial fibroblasts were divided into two experimental groups: a control group and an ACOX1-overexpression group. Each group consisted of six biological replicates. Total RNA was extracted from the cells and subjected to transcriptome sequencing. The resulting RNA-seq data were used to characterize ACOX1-associated transcriptional changes, with particular emphasis on inflammatory, metabolic, and extracellular-matrix-related pathways. These data provide transcriptomic evidence for investigating the role of ACOX1 in regulating the functional phenotype of synovial fibroblasts.2026/10/05GSE349121GSM10087339GSM10087337GSM10087348GSM10087338GSM10087346GSM10087347GSM10087344GSM10087345GSM10087342GSM10087343GSM10087340GSM1008734128330349121Mus musculus