GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE39nnn/GSE39069/primaryOK200TranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE39069GEOGSEfalseIkaros affects multiple lineages in hematopoietic development [RNA-Seq]Ikaros is a zinc finger transcription factor critical for proper hematopoietic development and tumor suppression in the lymphoid lineage. Here, we use the newly generated Ik-ZnF1-/- and Ik-ZnF4-/- mutant mice to study hematopoietic development in the BM. As an initial approach to study early hematopoietic development as well as non-lymphoid lineages, RNA-Seq was performed on "Hardy Fraction A" cells, without lineage depletion (B220+IgM-CD43+CD24-BP-1-), of wt and Ik-ZnF1-/- mice (two biological replicates of each). Ik-ZnF4-/- mice have extremely few cells in the "Hardy fraction A" gate, and only one RNA-Seq experiment was performed on this cell population, with strongly reduced reads/genome coverage.2026/05/30GSE39069GSM955180GSM955181GSM955177GSM955178GSM95517913112SRP01399339069Mus musculus