GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE50nnn/GSE50011/primaryOK2000000GenomicsHomo sapiensExpression profiling by arrayhttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE50011GEOGSE0falseTranscriptome analysis of HIV-infected peripheral blood monocytesImmunologic dysfunction, mediated via monocyte activity, has been implicated in the development of HIV-associated neurocognitive disorder (HAND). We hypothesized that transcriptome changes in peripheral blood monocytes relate to neurocognitive functioning in HIV+ individuals, and that such alterations could be useful as biomarkers of worsening HAND. METHODS: mRNA was isolated from the monocytes of 86 HIV+ adults and analyzed with the Illumina HT-12 v4 Expression BeadChip. Neurocognitive functioning, HAND diagnosis, and other clinical and virologic variables were determined.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 sapiens[24094461]