GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE59nnn/GSE59758/primaryOK2000000GenomicsHomo sapiensExpression profiling by arrayhttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE59758GEOGSE0falseGenome-wide shRNA screen to identify cellular regulators of the maintenance of HIV-1 latencyLatent HIV-1 infection represents a barrier to virus eradication as latent HIV-1 is impervious to the effects of antiretroviral drugs and can avoid detection by the host immune system. Strategies to clear latent HIV-1 infection in patients have so far failed in clinical trials to increase the decay rate of the latent reservoir underscoring the need for continued study of HIV-1 latency. In this study, a genome-wide RNAi screen was performed to probe cellular factors involved in maintaining HIV-1 latency in HeLa cells latently infected with an HIV-1 reporter virus.2016/07/14GSE59758GSM1446156GSM144615557059758Homo sapiens