{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE60nnn/GSE60621/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Homo sapiens"],"gds_type":["Expression profiling by array"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE60621"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Gene expression signature of Anagrelide in megakaryocytes","description":"Anagrelide is a cytoreductive agent used to lower platelet counts in essential thrombocythemia. Although the drug is known to selectively inhibit megakaryopoiesis, the molecular mechanism accounting for this activity has not been elucidated. In order to gain an insight into the mechanism of action of this drug we used microarrays to obtain a global gene expression signature of anagrelide","dates":{"publication":"2017/08/16"},"accession":"GSE60621","cross_references":{"GSM":["GSM1483853","GSM1483852","GSM1483851","GSM1483850","GSM1483849","GSM1483848"],"GPL":["570"],"GSE":["60621"],"taxon":["Homo sapiens"],"PMID":["[25851510]"]}}