GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE73nnn/GSE73576/primaryOK2000000GenomicsHomo sapiensGenome binding/occupancy profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE73576GEOGSE0false82-kDa ChAT and SATB1 ChIP-seq after vehicle or amyloid-beta exposureUsing chromatin immunoprecipitation and next-generation sequencing (ChIP-seq), we assessed the effects of acute exposure to oligomeric amyloid-beta on 82-kDa ChAT and SATB1 genome association in human SH-SY5Y neural cells, finding that Aβ-exposure increased 82-kDa ChAT and SATB1 association with gene promoters, introns and matrix attachment regions. We found that both SATB1 and 82-kDa ChAT associate with synapse and cell stress related genes after amyloid-beta exposure.2016/04/11GSE73576GSM1898105GSM1898104GSM1898103GSM1898102GSM1898101GSM18981009052SRP06432073576Homo sapiens[27052102]