GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE77nnn/GSE77626/primaryOK2000000GenomicsHomo sapiensExpression profiling by array; Third-party reanalysishttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE77626GEOGSE0falseFGFR1 SignatureThe gene encoding fibroblast growth factor receptor 1 (FGFR1) amplification is associated with poor prognosis in estrogen receptor positive (ER+) breast cancer, and thus represents a potential therapeutic target. Fluorescent in situ hybridization (FISH) has been used as the gold standard methodology for detection of FGFR1 amplification, but it is a relatively long labor-intensive procedure and not efficient to process a large number of patient samples, especially formalin fixed paraffin embedded (FFPE) samples. This study sought to identify genes discriminative at the mRNA level for FGFR1 amplification and to construct a multi-gene test to facilitate efficient screening for FGFR1 amplified ER+ breast tumors.2016/12/31GSE77626GSM2055371648077626Homo sapiens[27993329]