GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE86nnn/GSE86061/primaryOK200GenomicsHomo sapiensExpression profiling by arrayhttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE86061GEOGSEfalseExpression data of colon cancer COLO320DM cells and tankyrase inhibitor-resistant variant 320-IWR cellsWnt/β-catenin signaling is activated in colorectal cancer (CRC) and is involved in CRC growth. Tankyrase, a poly(ADP-ribose) polymerase family member, destabilizes Axin and positively regulates the Wnt/β-catenin signaling. Tankyrase inhibitors efficiently suppress CRC cell proliferation. We established 320-IWR cells, which showed resistance to tankyrase inhibitor IWR-1, from human CRC COLO-320DM cells. We analyzed gene expression profile of 320-IWR cells (320IWR_1,_2) and parental COLO-320DM cells (COLO320_1,_2).2016/11/01GSE86061GSM2292754GSM2292751GSM2292753GSM229275257086061Homo sapiens[28615517]