GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE88nnn/GSE88798/primaryOK2000000GenomicsArabidopsis thalianaExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE88798GEOGSE0falseTime-resolved transcriptome analysis with genetic perturbations reveals a critical time window for effective plant immunityPathogen invasion in plants is associated with transcriptional reprogramming. Enigmatically, plants induce similar transcriptome responses upon infection by virulent or avirulent pathogens. This renders the importance of transcriptional reprogramming for immunity obscure. Here, using RNA-seq, we generate time-series transcriptome data coupled with genetic perturbations to reveal temporal dynamics upon infection by virulent or avirulent strains of a bacterial pathogen, Pseudomonas syringae, in Arabidopsis thaliana. Fast and sustained transcriptional reprogramming occurs upon infection with avirulent strains while virulent strain infection leads to a slower response with comparable gene expression patterns and magnitudes. Importantly, transcriptome analysis of resistant and susceptible mutants responding to avirulent strains links delayed transcriptional reprogramming to compromised immunity. Taken together, our results pinpoint the early critical time window of transcriptional reprogramming for establishing effective immunity against the bacterial pathogen.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 thaliana[29794063]