{"database":"GNPS","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://massive-ftp.ucsd.edu/v07/MSV000094574/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Metabolomics"],"submitter":["Benjamin C Orsburn"],"instrument_platform":["Q Exactive"],"species":["Homo Sapiens (ncbitaxon:9606)"],"full_dataset_link":["https://massive.ucsd.edu/ProteoSAFe/dataset.jsp?task=518f8428662d45d1992d0b7525b2bd36"],"submitter_email":["borsbur1@jhmi.edu"],"submitter_affiliation":["Johns Hopkins"],"sample_protocol":[""],"repository":["GNPS"],"file_size":["45"],"ptm_modification":["MS:1002864 - No post-translational-modifications are included in the identified peptides of this dataset"],"data_protocol":[""],"additional_accession":[]},"is_claimable":false,"name":"GNPS - Analysis of nicotinamide based anti-aging supplements in 2024 by untargeted high resolution mass spectrometry","description":"\"Anti-aging\" supplements purported to contain nicotinamide based compounds were obtained from a variety of sources. Samples were extracted in a solution of 60% methanol at a 1:20 to 1:100 ratio based on pilot tests on solubilization of material. Extracts were clarified by high speed centrifugation, dried by speedvac and diluted to a 1:100 to 1:500 g/g ratio of the original material in 5% acetonitrile in LCMS grade water. Samples were analyzed on a Q Exactive Classic system coupled to a Dionex UHPLC using a 15cm x 2.1mm HyperSil gold column with 1.5um particles (Thermo, all). A 20 minute method with a data dependent top 3 method was used with each sample analyzed in triplicate, separately in each polarity. The output files were analyzed in Compound Discoverer 3.3 SP2 using a combination of libraries as described in the manuscript. Standards were obtained from MilliPore Sigma for Nicotinamide and derivatives for retention time matching and concentation estimations. ","dates":{"publication":"Sat Apr 20 06:27:00 BST 2024"},"accession":"MSV000094574","cross_references":{}}