GPMDB00213OtherVerdier Y, et al.InstrumentNot AvailableNot availableFlyyann.verdier@espci.frNot availablehttp://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017750http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017752http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017751http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017710http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017754http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017753http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017679http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017712http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017756http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017755http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017711http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017678http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017714http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017758http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017757http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017713http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017716http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017715http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017759http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017718http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017717http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017719http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017680http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017682http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017681http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017741http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017740http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017743http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017742http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017701http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017745http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017700http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017744http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017747http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017703http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017746http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017702http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017749http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017705http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017748http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017704http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017707http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017706http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017709http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017708http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017772http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017695http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017771http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017694http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017697http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017730http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017773http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017696http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017732http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017699http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017698http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017731http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017734http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017733http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017736http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017735http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017738http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017737http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017739http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017684http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017761http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017683http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017760http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017763http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017762http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017685http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017721http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017688http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017765http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017720http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017764http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017687http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017767http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017723http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017722http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017689http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017766http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017725http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017769http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017724http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017768http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017727http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017726http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017729http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017728http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017691http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017690http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017693http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017770http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM11210017692SMBP CNRSNot availableGPMDBDrosophila Fruit, Drosophila (Drosophila), Drosophila, Drosophila Fallen, Drosophila Fruit Fly, Drosophilas, fruit fly <Drosophila>, Fly, Fruit Fly, fruit flies, Drosophila Fruit Flies., Flies, 1823, Fruit FliesTGF1a, knobbly, Deacura, Materials, determination, HSN1E, Effects, Slf, Biotine, Somatomedin-C, Fused, Medebiotin, EA1, Gene, FPH2, Vitamin H, MLR-3, electronic data file, mcIAP1, Long Term, period, Readability, AIM, RNF48, RNF49, Biotin, kinky, Hot, 4beta, Gene Products, Line, Heat, early activation antigen CD69, 6aalpha))-, Gelfert, Effect, Pglyrp, Biotin Hermes, mKIAA0733, cIAP2, Genetic, cIAP1, cIAP-2, A530078N03Rik, cIAP-1, Longterm, activation inducer molecule, PGRP, B430101B05, somatomedin-C, SF, min, TAK1, Tak1, cell line cell, Kitl, proteins, Tr4, Long-Term, HIAP1, 1110030N06Rik, HIAP2, Mast cell growth factor, cell line, Biotinylations, MEKK7, TAB-2, leukocyte surface antigen Leu-23, Am2, Api2, Hermes, Api1, h, PGRP-S, IGF1, AI316800, Mechano growth factor, C-type lectin domain family 2 member C, mKIAA4145, fused to, Long-Term Effect, Soluble KIT ligand, C87327, mKIAA1278, TR4, Kb, Sl, Long-Term Effects, Ki, IGF-I, Medobiotin, data, steel factor, Birc3, Birc2, Rombellin, AW107670, hematopoietic growth factor KL, Map3k7ip2, Proteins, DNMT, PGLYRP, Cell Lines, Longterm Effect, somatomedin, Roche, Biotin Gelfert, cell_line, MIAP2, MCMT, MIAP1, Cistrons, Cell, sKITLG, B930045J24, 4-d)imidazole-4-pentanoic acid, (3aS-(3aalpha, Imd, IMD, BL-AC/P26, polypeptide, Axin, AW146227, Temperatures, mechano growth factor, chemical analysis, Protein, Long Term Effects, Pgrp, computer data file, MIHB, Biotin Ratiopharm, Genetic Materials, MIHC, Igf-1, activation, Genetic Material, TNFSF3L, Biodermatin, Lines, CXXC9, early T-cell activation antigen p60, Biotin-Ratiopharm, 1H-Thieno(3, Temperature, ADCADN, SHEP7, h., Biotine Roche, Gabunat, mast cell growth factor, Stem cell factor, FU, hexahydro-2-oxo-, Understanding, IAP2, STAT5, TAG7, merged with, IAP1, Longterm Effects, Protein Gene Products, Gene Proteins, stem cell factor, KL-1, GP32/28, Material, Imdn, joined with, MGF, c-Kit ligand, CHTD2, Fu, KITLG, Hot Temperatures, Cistron, assay, PGRPS, SCF, fused, 1700112N14Rik, CD69, coalesced, Biokur, time, CLEC2C, MAP3K7IP2210http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM112100177603dbgap_ncbi~0patentfamilies~0rfam~0merops~0complex-portal~0uniprot~0wormbaseparasite~0embl-covid19~0reactome~0emdb~0wgs_masters~0ebiweb_resources~0opentargets_genetics~0biomodels_all~0ipd-mhc~0ebiweb_teams~0taxonomy~0genome_assembly~0sc-experiments~0ebiweb_people~0enzymeportal_enzymes~0ipd-nhkir~0cellosaurus~0pdbe~0chebi~0patentproteins~0interpro7~0uniref~0chembl~0pdbekb~0gpcrdb~0hgnc~0sc-genes~0intact~0rhea~0ebiweb_training~0alphafold~0imgt-hla~0patentnucleotides~0ensemblroot~0eva_studies~0non-coding~0europepmc~0identifiers_registry~0pdbechem~0hpa-covid19~0eva-variants-covid19~0biosamples~0gwas_catalog~0biotools~0tls_masters~0mesh~0coding~0sra~0opentargets~0efo~0embl-pathogen~0project~0pride~1human_diseases~0geo_datasets~0embl~0treefam~0uniparc~0ols~0dgva~0intenz~0go~0tsa_masters~0biosamples-covid19~0ebiweb_corporate~0omim~0lrg~0earlycause-molecular-sequences~0ipd-kir~0empiar~0rnacentral~0orcid_data_claims~0gpmdb~1lineage-covid19~0metagenomics~0pfam~0pride archive~1varsite~00Resource Reanalysis0.00.00.0064774830351634790.01.0falseDrosophila immune responseData from ProteomeXchange, PXD ID: PXD000129. Data file: TAB_10min_C_F054940.mgf. From ProteomeXchange: {{i}} ... To gain a better understanding of the molecular machineries underlying the pleiotropic functions of this pathway, we have developed a proteomics analysis. Our first aim was to identify the proteins interacting with the 11 canonical members (PGRP-LC, PGRP-LE, IMD, BG4 (dFADD), DREDD, TAK1, TAB2, IAP2, IRD5 (DmIKKbeta), KEY (DmIKKgamma), and RELISH) previously shown to be involved in the activation of the IMD pathway. Each protein was fused N-terminally or C-terminally with a biotin tag and was stably expressed in S2 cells previously subjected to stable integration of the bacterial enzyme BirA to allow for biotinylation of the tags. In total, we established 22 stable transformant cell lines (11 genes x 2 tag locations), which were individually stimulated by heat-killed E.coli before harvest at 4 different time points (t=0 min, 10 min, 2 hour, and 8 hour) ...{{/i}}2013-05-22GPM11210017760PXD000129PXD000129