{"database":"GPMDB","file_versions":[],"scores":{"citationCount":0,"reanalysisCount":0,"viewCount":24,"searchCount":3},"additional":{"omics_type":["Other"],"submitter":["Sleno L, et al."],"instrument_platform":["Instrument"],"disease":["Not Available"],"brenda_tissue":["Not available"],"species":["Mus_musculus_viruses, Mouse"],"submitter_mail":["sleno.lekha@uqam.ca"],"publication":["Not available"],"model":["http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM32320014347","http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM32320014348","http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM32320014345"],"submitter_affiliation":["Bioanalytical Mass Spectrometry Research Group, Chemistry Department, Universite du Quebec"],"cell_type":["Not available"],"repository":["GPMDB"],"name_synonyms":["LC-MS2, liquid chromatography tandem mass spectroscopy, Mus musculus, 3.4.22.-, LCMSMS, Caspase-14 subunit p10, Laboratory, Swiss, Microsome, mice, Entire liver, Mus domesticus, mouse, Swiss Mouse, LC-MS/MS, iecur, House Mice, Swiss Mice, mini-ICE, Caspase-14 subunit p19, CASP-14, \"mouse\" EXACT common_name [], MICE, House Mouse, mice C57BL/6xCBA/CaJ hybrid, Mus muscaris, Laboratory Mice, domesticus, jecur, \"house mouse\" EXACT genbank_common_name [], \"Mus muscaris\" RELATED misnomer [], Livers, LC/MS/MS, House, Mus, liquid chromatography-tandem mass spectroscopy, Mini-ICE, LC-MSMS, proteomic analysis, Mus musculus domesticus, liquid chromatography tandem mass spectrometry, \"mice C57BL/6xCBA/CaJ hybrid\" RELATED misspelling [], LC-MS-MS., Mouse, house mouse, Mice, Laboratory Mouse"],"description_synonyms":["biochemical pathways, liquid chromatography tandem mass spectroscopy, 3.4.22.-, Metabolic Process, Toxinology, human being, Bhlha41, determination, Prospecting, Laboratory, Slf, Processes, Mus domesticus, Somatomedin-C, Metabolic Concepts, Toxicology, bHLHa48, Gene, FPH2, mini-ICE, CASP-14, Metabolic Processes, Homo sapiense, SCXB, House Mouse, SCXA, LC-MS-MS, jecur, peptide, rat, Rattus sp. strain Wistar, Homo spaiens, Homo sapien, Rats, Roles, House, Metabolism, Drug Prospecting, Mammals, \"Rattus rattiscus\" RELATED misnomer [], Homo sapians, LC-MSMS, Exchange, Gene Products, Concepts, Mus musculus domesticus, Norway rat, Rattus rattiscus, Metabolism Concept, Phenomenon, Toxicologies, Metabolism Phenomena, Mice, Evidence-Based Toxicologies, Based Toxicologies, brown rat, \"Gunn rats\" RELATED misnomer [], Homo sapients, LCMSMS, catabolism, Microsome, Swiss, Evidence Based Toxicologies, somatomedin-C, SF, iecur, Metabolic Concept, \"brown rat\" EXACT common_name [], Kitl, Swiss Mice, metabolic process resulting in cell growth, proteins, \"Rattus norvegicus8\" RELATED misspelling [], \"mouse\" EXACT common_name [], man, Mast cell growth factor, \"Mus muscaris\" RELATED misnomer [], Homo sapience, IGF1, Homo sampiens, Role Concepts, Mechano growth factor, biotransformation, \"mice C57BL/6xCBA/CaJ hybrid\" RELATED misspelling [], Soluble KIT ligand, house mouse, Sl, Catabolism, Home sapiens, Rattus norvegicus8, LC-MS2, incorporation, IGF-I, data, steel factor, degradation, Process, hematopoietic growth factor KL, Entire liver, metabolism resulting in cell growth, Proteins, Based Toxicology, LC-MS/MS, mouse, somatomedin, sKITLG, mice C57BL/6xCBA/CaJ hybrid, Mus muscaris, Concept, Metabolic Phenomena, polypeptide, Metabolism Concepts, LC/MS/MS, Experiment, Role Concept, Discovery, Rattus norwegicus, Mus, Homo sapian, species., mechano growth factor, BB114693, chemical analysis, Mini-ICE, Protein, Phenomena, Role, \"rat\" EXACT common_name [], \"Rattus sp. strain Wistar\" EXACT equivalent_name [], Homo sapeins, Igf-1, metabolism, Metabolic Phenomenon, Evidence-Based Toxicology, Evidence Based, Mus musculus, SHEP7, mobilization, multicellular organism metabolic process, \"rats\" EXACT common_name [], mast cell growth factor, biodegradation, Caspase-14 subunit p10, Metabolic, mice, Evidence Based Toxicology, Stem cell factor, Swiss Mouse, Humo sapiens, House Mice, Caspase-14 subunit p19, STAT5, Evidence, MICE, rats, Homo sapines, turnover, human, Laboratory Mice, domesticus, Drug, Protein Gene Products, \"house mouse\" EXACT genbank_common_name [], Livers, Gene Proteins, stem cell factor, single-organism metabolic process, Homo spiens, KL-1, \"human\" EXACT genbank_common_name [], Ion, liquid chromatography-tandem mass spectroscopy, \"Norway rat\" EXACT genbank_common_name [], MGF, c-Kit ligand, \"Rattus norwegicus\" RELATED misspelling [], KITLG, liquid chromatography tandem mass spectrometry, Mouse, assay, SCF, Evidence-Based, Proteomes, Laboratory Mouse, Scl, Anabolism, Gunn rats"],"view_count":["24"],"citation_count":["0"],"full_dataset_link":["http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM32320014347"],"search_count":["3"],"search_domains":["dbgap_ncbi~0","patentfamilies~0","rfam~0","merops~0","complex-portal~0","uniprot~0","wormbaseparasite~0","embl-covid19~0","reactome~0","emdb~0","wgs_masters~0","ebiweb_resources~0","opentargets_genetics~0","biomodels_all~0","ipd-mhc~0","ebiweb_teams~0","taxonomy~0","genome_assembly~0","sc-experiments~0","ebiweb_people~0","enzymeportal_enzymes~0","ipd-nhkir~0","cellosaurus~0","pdbe~0","chebi~0","patentproteins~0","interpro7~0","uniref~0","chembl~0","pdbekb~0","gpcrdb~0","hgnc~0","sc-genes~0","intact~0","rhea~0","ebiweb_training~0","alphafold~0","imgt-hla~0","patentnucleotides~0","ensemblroot~0","eva_studies~0","non-coding~0","europepmc~0","identifiers_registry~0","pdbechem~0","hpa-covid19~0","eva-variants-covid19~0","biosamples~0","gwas_catalog~0","biotools~0","tls_masters~0","mesh~0","coding~0","sra~0","opentargets~0","efo~0","embl-pathogen~0","project~0","pride~1","human_diseases~0","geo_datasets~0","embl~0","treefam~0","uniparc~0","ols~0","dgva~0","intenz~0","go~0","tsa_masters~0","biosamples-covid19~0","ebiweb_corporate~0","omim~0","lrg~0","earlycause-molecular-sequences~0","ipd-kir~0","empiar~0","rnacentral~0","orcid_data_claims~0","gpmdb~1","lineage-covid19~0","metagenomics~0","pfam~0","pride archive~1","varsite~0"],"reanalysis_count":["0"],"submitter_keywords":["Resource Reanalysis"],"citation_count_scaled":["0.0"],"reanalysis_count_scaled":["0.0"],"view_count_scaled":["0.007402837754472548"],"download_count_scaled":["0.0"],"normalized_connections":["1.0"],"additional_accession":[]},"is_claimable":false,"name":"Proteomic Analysis of Mouse Liver Microsomes by 2D-LC-MSMS","description":"Data from ProteomeXchange, PXD ID: PXD000731. Experiment: pepsin, file: MMP_1.mgf. Data published as part of EuPA Open Proteomics Volume 6, March 2015, 16-27  . From the Abstract: {{i}} ... Liver plays a key role in metabolism and detoxification, therefore analysis of its proteome is relevant for toxicology and drug discovery studies. To optimize for high proteome coverage, protein and peptide-level ion exchange fractionation were assessed using rat liver microsomes and S9 fractions. 2D-(SCX-RP)-LC-MS/MS analysis with peptide fractionation was subsequently employed for rat, mouse and human samples, yielding between 1400 and 1939 identified proteins, 58% of which were shared between species, and with relatively high sequence coverage. {{/i}}","dates":{"submission":"2015-03-26"},"accession":"GPM32320014347","cross_references":{"Pride":["PXD000731"],"pride":[],"Pride Archive":["PXD000731"]}}