{"database":"GPMDB","file_versions":[],"scores":{"citationCount":0,"reanalysisCount":0,"viewCount":21,"searchCount":3},"additional":{"omics_type":["Other"],"submitter":["Sleno L, et al."],"instrument_platform":["Instrument"],"disease":["Not Available"],"brenda_tissue":["Not available"],"species":["Mus_musculus_viruses, Mouse"],"submitter_mail":["sleno.lekha@uqam.ca"],"publication":["Not available"],"model":["http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM32320014350","http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM32320014351","http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM32320014352"],"submitter_affiliation":["Bioanalytical Mass Spectrometry Research Group, Chemistry Department, Universite du Quebec"],"cell_type":["Not available"],"repository":["GPMDB"],"name_synonyms":["LC-MS2, liquid chromatography tandem mass spectroscopy, Mus musculus, 3.4.22.-, LCMSMS, Caspase-14 subunit p10, Laboratory, Swiss, mice, Entire liver, Mus domesticus, mouse, Swiss Mouse, LC-MS/MS, iecur, House Mice, Swiss Mice, mini-ICE, Caspase-14 subunit p19, CASP-14, \"mouse\" EXACT common_name [], MICE, House Mouse, mice C57BL/6xCBA/CaJ hybrid, Mus muscaris, Laboratory Mice, domesticus, jecur, \"house mouse\" EXACT genbank_common_name [], \"Mus muscaris\" RELATED misnomer [], Livers, LC/MS/MS, House, Mus, liquid chromatography-tandem mass spectroscopy, Mini-ICE, LC-MSMS, proteomic analysis, Mus musculus domesticus, liquid chromatography tandem mass spectrometry, \"mice C57BL/6xCBA/CaJ hybrid\" RELATED misspelling [], LC-MS-MS., Mouse, house mouse, Mice, Laboratory Mouse"],"description_synonyms":["biochemical pathways, liquid chromatography tandem mass spectroscopy, Metabolic Process, MSPL, PSP94, Bhlha41, determination, Prospecting, Laboratory, MSPS, Mus domesticus, NF15S2, Somatomedin-C, Metabolic Concepts, bHLHa48, CASP-14, Homo sapiense, House Mouse, peptide, HGFL, rat, Homo sapien, Roles, Drug Prospecting, Mammals, \"Rattus rattiscus\" RELATED misnomer [], Homo sapians, Exchange, Concepts, Norway rat, Metabolism Concept, Phenomenon, MSPB, \"Gunn rats\" RELATED misnomer [], Homo sapients, LCMSMS, catabolism, Microsome, Evidence Based Toxicologies, Hepatocyte growth factor-like protein beta chain, somatomedin-C, SF, iecur, \"brown rat\" EXACT common_name [], Kitl, Swiss Mice, metabolic process resulting in cell growth, proteins, \"Rattus norvegicus8\" RELATED misspelling [], Mast cell growth factor, Homo sapience, IGF1, DNF15S2, Role Concepts, Mechano growth factor, biotransformation, \"mice C57BL/6xCBA/CaJ hybrid\" RELATED misspelling [], Soluble KIT ligand, house mouse, Sl, Catabolism, Home sapiens, LC-MS2, PSP57, incorporation, IGF-I, steel factor, Process, metabolism resulting in cell growth, LC-MS/MS, mouse, somatomedin, sKITLG, mice C57BL/6xCBA/CaJ hybrid, Role Concept, Rattus norwegicus, Macrophage-stimulating protein, Homo sapian, PSP, species., mechano growth factor, BB114693, Mini-ICE, Role, \"Rattus sp. strain Wistar\" EXACT equivalent_name [], Igf-1, Evidence-Based Toxicology, Evidence Based, Mus musculus, SHEP7, \"rats\" EXACT common_name [], mast cell growth factor, Caspase-14 subunit p10, Macrophage stimulatory protein, mice, Stem cell factor, Swiss Mouse, Caspase-14 subunit p19, STAT5, Evidence, MICE, PN44, rats, Homo sapines, turnover, human, domesticus, stem cell factor, KL-1, liquid chromatography-tandem mass spectroscopy, KITLG, Mouse, Evidence-Based, Proteomes, PSP-94, 3.4.22.-, Toxinology, human being, Slf, Processes, Toxicology, Gene, FPH2, mini-ICE, Metabolic Processes, SCXB, SCXA, LC-MS-MS, jecur, Rattus sp. strain Wistar, Homo spaiens, Rats, House, Metabolism, LC-MSMS, Gene Products, Mus musculus domesticus, Rattus rattiscus, Hepatocyte growth factor-like protein alpha chain, Toxicologies, Metabolism Phenomena, Mice, Evidence-Based Toxicologies, Based Toxicologies, brown rat, GP63, Swiss, Metabolic Concept, \"mouse\" EXACT common_name [], man, \"Mus muscaris\" RELATED misnomer [], TMPRSS11, MSP, Homo sampiens, Rattus norvegicus8, data, HPC13, degradation, hematopoietic growth factor KL, Entire liver, Proteins, Based Toxicology, Mus muscaris, PRPS, Concept, Metabolic Phenomena, polypeptide, Metabolism Concepts, LC/MS/MS, Experiment, Discovery, Mus, chemical analysis, Protein, Phenomena, IX14, \"rat\" EXACT common_name [], Homo sapeins, D3F15S2, metabolism, Metabolic Phenomenon, IGBF, mobilization, multicellular organism metabolic process, biodegradation, Metabolic, Evidence Based Toxicology, INV, Humo sapiens, House Mice, Laboratory Mice, Drug, Protein Gene Products, \"house mouse\" EXACT genbank_common_name [], Livers, Gene Proteins, single-organism metabolic process, Homo spiens, \"human\" EXACT genbank_common_name [], Ion, \"Norway rat\" EXACT genbank_common_name [], MGF, c-Kit ligand, \"Rattus norwegicus\" RELATED misspelling [], liquid chromatography tandem mass spectrometry, assay, SCF, Laboratory Mouse, Scl, Anabolism, Gunn rats"],"view_count":["21"],"citation_count":["0"],"full_dataset_link":["http://gpmdb.thegpm.org/~/dblist_gpmnum/gpmnum=GPM32320014350"],"search_count":["3"],"search_domains":["dbgap_ncbi~0","patentfamilies~0","rfam~0","merops~0","complex-portal~0","uniprot~0","wormbaseparasite~0","embl-covid19~0","reactome~0","emdb~0","wgs_masters~0","ebiweb_resources~0","opentargets_genetics~0","biomodels_all~0","ipd-mhc~0","ebiweb_teams~0","taxonomy~0","genome_assembly~0","sc-experiments~0","ebiweb_people~0","enzymeportal_enzymes~0","ipd-nhkir~0","cellosaurus~0","pdbe~0","chebi~0","patentproteins~0","interpro7~0","uniref~0","chembl~0","pdbekb~0","gpcrdb~0","hgnc~0","sc-genes~0","intact~0","rhea~0","ebiweb_training~0","alphafold~0","imgt-hla~0","patentnucleotides~0","ensemblroot~0","eva_studies~0","non-coding~0","europepmc~0","identifiers_registry~0","pdbechem~0","hpa-covid19~0","eva-variants-covid19~0","biosamples~0","gwas_catalog~0","biotools~0","tls_masters~0","mesh~0","coding~0","sra~0","opentargets~0","efo~0","embl-pathogen~0","project~0","pride~1","human_diseases~0","geo_datasets~0","embl~0","treefam~0","uniparc~0","ols~0","dgva~0","intenz~0","go~0","tsa_masters~0","biosamples-covid19~0","ebiweb_corporate~0","omim~0","lrg~0","earlycause-molecular-sequences~0","ipd-kir~0","empiar~0","rnacentral~0","orcid_data_claims~0","gpmdb~1","lineage-covid19~0","metagenomics~0","pfam~0","pride archive~1","varsite~0"],"reanalysis_count":["0"],"submitter_keywords":["Resource Reanalysis"],"citation_count_scaled":["0.0"],"reanalysis_count_scaled":["0.0"],"view_count_scaled":["0.006477483035163479"],"download_count_scaled":["0.0"],"normalized_connections":["1.0"],"additional_accession":[]},"is_claimable":false,"name":"Proteomic Analysis of Mouse Liver S9 Fraction by 2D-LC-MSMS","description":"Data from ProteomeXchange, PXD ID: PXD000731. Experiment: pepsin, file: MSP_2.mgf. Data published as part of EuPA Open Proteomics Volume 6, March 2015, 16-27  . From the Abstract: {{i}} ... Liver plays a key role in metabolism and detoxification, therefore analysis of its proteome is relevant for toxicology and drug discovery studies. To optimize for high proteome coverage, protein and peptide-level ion exchange fractionation were assessed using rat liver microsomes and S9 fractions. 2D-(SCX-RP)-LC-MS/MS analysis with peptide fractionation was subsequently employed for rat, mouse and human samples, yielding between 1400 and 1939 identified proteins, 58% of which were shared between species, and with relatively high sequence coverage. {{/i}}","dates":{"submission":"2015-03-26"},"accession":"GPM32320014350","cross_references":{"Pride":["PXD000731"],"pride":[],"Pride Archive":["PXD000731"]}}