{"database":"iProX","file_versions":[],"scores":null,"additional":{"omics_type":["Proteomics"],"submitter":["Dandan Hu"],"species":["Toxoplasma Gondii Me49"],"full_dataset_link":["http://www.iprox.org/page/project.html?id=IPX0010936000"],"submitter_email":["hudandan@gxu.edu.cn"],"submitter_affiliation":["College of Animal Science and Technology, Guangxi University"],"sample_protocol":[""],"repository":["iProX"],"data_protocol":[""],"name_synonyms":["Human, gondius, Human Reproductive Index, Reproductive, Reproductive Index, Indices, Period, Index, Indexes, Human Reproductive Indices, Reproductive Periods., reproductive physiological process, SWI-SNF complex, Toxoplasma, Periods, Reproductive Period, Toxoplasma gondii, Toxoplasmas, Human Reproductive Indexes, Toxoplasma gondius, Human Reproductive, Reproductive Indices"],"description_synonyms":["Base Editing, CRISPR Locus, CRISPR Loci, CRISPR-Cas Loci, DIP1, rasGAP, Materials, Clustered Regularly Interspaced Short Palindromic Repeat, Procedures, Activity, determination, Transcriptome Profile, Laboratory, CRISPR Spacer, GAPDH II, Disassembly, Chromatin Disassemblies, 10538, Gene Expression Profile, GTPase-activating protein, Gene, Gapdh13F, CRISPR Array, Profiles, GAP1, Chromatin Assembly, gondius, GCIP, Techniques, GADPH, CG8893, Method, gap1, Studies, PKWS, Projections and Predictions, Merozoite, Chromatin Disassembly, Research Activity, Sprains, FBgn 32821, Laboratory Research, Technique, Arrays, ATP-dependent chromatin remodeling, CRISPR Spacers, Priorities, study, anatomical systems, Genetic, RasGAP, Research, Elements, Profile, Gapd, GA3PDH, SWI-SNF complex, Gap 1, Chromatin Remodeling, Predictions and Projections., mip, Futurology, procedures, CRISPR Spacer Sequence, GAPDH2, Signatures, CRISPR Sequences, CRISPR Cluster, CRISPR, Study, CRISPRs, CRISPR-Cas Locus, d-CdGAPr, Gapdh-2, Methodological Studies, Expression Signature, Loci, Transcriptomes, nucleosome remodeling complex, CM-AVM, CG6721, Toxoplasma gondii, Toxoplasmas, Strains, Development and Research, Research Priority, DmelCG8893, SSEC-8, Spacer Sequence, CRISPR Spacer Sequences, CRISPR Clusters, CRISPR Sequence, Transcriptome, Sprain, Expression Profiles, Research Priorities, CRISPR Arrays, CRISPR-Cas, Clusters, Procedure, RASGAP, Cistrons, RASA, Genome Editing, Sequences, Gene Expression, CRISPR Element, Priority, chromatin remodelling complex, Sequence, Gapdh, Expression Signatures, Gene Expression Signatures, chemical analysis, sxt, Strain, CRISPR Elements, Research Activities, Genetic Materials, Gene Expression Signature, Spacer, techniques, rI533, GAP, Gap, p120GAP, p120RASGAP, Expression Profile, Genetic Material, GAPDH, Transcriptome Profiles, Research and Development, Ras-GAP, Chromatin, Epistemology, CG10538, Element, DmelCG6721, Editing, Remodeling, Chromatin Modeling, DmelCG10538, SECC-8, INSDC_feature:gene, Methodological, gap, Toxoplasma gondius, CMAVM, Methodological Study, Locus, ATP-dependent chromatin remodelling, Activities, AU022347, Cluster, Material, Maid, Gene Expression Profiles, Ras p21 protein activator, Spacers, Base, Array, Toxoplasma, CRISPR Cas Loci, Cistron, Spacer Sequences, assay, chromatin remodeling complex, Signature, Future, Strains and Sprains, Genome, methodology"],"additional_accession":[]},"is_claimable":false,"name":"Identification of the SWI/SNF complex of Toxoplasma gondii and its molecular mechanism regulating fissional reproduction","description":"The purpose of this study was to identify the composition of the chromatin remodeling complex SWI/SNF complex, and then to screen some genes from them, and construct mAID system knockout strains by CRISPR-Cas9 gene editing methods, and to carry out phenotypic experiments and transcriptome differentialomics analysis. It is speculated that this gene may regulate the transformation of Toxoplasma gondii from tachyzoites to merozoites. The above studies fill the knowledge gap for the functional exploration of chromatin remodeling complexes on Toxoplasma gondii and provide a theoretical basis for further research in the future.","dates":{"publication":"Sun Jan 26 00:00:00 GMT 2025"},"accession":"PXD060237","cross_references":{"TAXONOMY":["508771"]}}